Lunglmayr G, Kratzik C, Biegelmayer C
Wien Klin Wochenschr. 1984 Sep 14;96(17):651-4.
Repeated blood sampling at 10-minute intervals over a 4-hour period (15.00 until 19.00) for simultaneous determination of FSH, LH and testosterone was carried out in 7 normospermic men and 8 patients presenting with idiopathic oligozoospermia. Fluctuations of LH and testosterone were observed within the 4-hour sampling period. Only minor alterations of FSH were found. Planimetric assessment of the areas under the curves of FSH, LH and testosterone did not show any significant difference in FSH. Testosterone was found to be significantly decreased in the oligospermic group (p less than 0.025), while LH showed a tendency to be increased (p less than 0.1). These results point out that single determinations of LH and testosterone do not provide exact information, due to the wide range of hormone fluctuation. Serial sampling of the hormones demonstrates Leydig cell dysfunction in patients with moderate idiopathic oligozoospermia.
在7名精子正常的男性和8名特发性少精子症患者中，于4小时内（15:00至19:00）每隔10分钟重复采血，以同时测定促卵泡激素（FSH）、促黄体生成素（LH）和睾酮。在4小时的采样期内观察到LH和睾酮的波动。仅发现FSH有轻微变化。对FSH、LH和睾酮曲线下面积进行的平面测量评估显示，FSH无显著差异。发现少精子症组的睾酮显著降低（p<0.025），而LH有升高趋势（p<0.1）。这些结果指出，由于激素波动范围广，单次测定LH和睾酮并不能提供准确信息。对这些激素进行连续采样表明，中度特发性少精子症患者存在睾丸间质细胞功能障碍。
