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二尖瓣疾病各种治疗方法的比较评估。关于使用斯塔尔人工瓣膜、比约克人工瓣膜、生物瓣膜和瓣膜重建术对4组各100例患者进行手术的情况

[Comparative evaluation of various methods of treatment of mitral valve diseases. Apropos of 4 series of 100 patients operated on using the Starr prosthesis, Bjork prosthesis, bioprosthesis and valve reconstruction].

作者信息

Perier P, Deloche A, Rossand P, Fabiani J N, Bessou J P, Bourezak H, Chachques J C, d'Allaines C, Blondeau P, Carpentier A

出版信息

Arch Mal Coeur Vaiss. 1984 Dec;77(13):1517-24.

PMID:6440502
Abstract

The results of 4 groups of 100 patients undergoing mitral valvuloplasty (group I), isolated mitral valve replacement by a bioprosthesis (group II), a Starr-Edwards prosthesis (group III) and a Björk prosthesis (group IV) between 1974 and 1977 were compared. The selection of patients for each group was identical and made according to strict criteria. The average age was between 47.1 +/- 12.5 years and 51.8 +/- 10.5 years according to the particular group; the average functional classification was 2.4 +/- 0.4 to 2.5 +/- 0.6; the average cardiothoracic ratio was 0.58 +/- 0.07. Most patients were in atrial fibrillation. Ninety-seven per cent of patients were followed-up by questionnaires. The results were expressed with respect to simple clinical events used in all previously reported series. The long-term mortality was identical in the 3 groups undergoing valve replacement (40 p. 100 at 7 years) but was much less in the group undergoing valvuloplasty (18 p. 100 at 7 years). The mortality rate due to valvular problems was significantly less in the valvuloplasty group (2 p. 100 at 7 years) than in the groups with mechanical prostheses (20 p. 100 at 7 years). Intermediate results were observed in the bioprosthetic group (9 p. 100 at 7 years). Thrombo-embolism was significantly less common in the groups undergoing valvuloplasty and bioprosthetic valve replacement (2 p. 100 and 6 p. 100 at 7 years) than in the group with Starr-Edwards and Björk prostheses (30 p. 100 and 32 p. 100 at 7 years).(ABSTRACT TRUNCATED AT 250 WORDS)

摘要

比较了1974年至1977年间4组各100例接受二尖瓣成形术的患者(第一组)、接受生物瓣单纯二尖瓣置换术的患者(第二组)、接受Starr-Edwards人工瓣膜置换术的患者(第三组)和接受Björk人工瓣膜置换术的患者(第四组)的结果。每组患者的选择相同,且均依据严格标准进行。根据具体分组,平均年龄在47.1±12.5岁至51.8±10.5岁之间;平均功能分级为2.4±0.4至2.5±0.6;平均心胸比率为0.58±0.07。大多数患者为房颤。97%的患者通过问卷调查进行随访。结果依据所有先前报道系列中使用的简单临床事件来表述。接受瓣膜置换的3组患者的长期死亡率相同(7年时为40%),但接受二尖瓣成形术的组死亡率要低得多(7年时为18%)。二尖瓣成形术组因瓣膜问题导致的死亡率(7年时为2%)显著低于使用机械瓣膜的组(7年时为20%)。生物瓣组观察到的中期结果(7年时为9%)。二尖瓣成形术组和生物瓣置换术组的血栓栓塞发生率(7年时分别为2%和6%)显著低于接受Starr-Edwards和Björk人工瓣膜置换术的组(7年时分别为30%和32%)。(摘要截断于250字)

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