Svigos J M
Aust N Z J Obstet Gynaecol. 1984 Aug;24(3):182-5. doi: 10.1111/j.1479-828x.1984.tb01485.x.
A retrospective study of 75 pregnant epileptic women compared with a parity, age and socioeconomic matched control group of women is presented. Deterioration of control of epilepsy during pregnancy occurred in 24% of women. Statistically significant obstetric complications noted were anaemia, premature labour, premature rupture of the membranes and postpartum haemorrhage. There was 2.5-fold increase in the incidence of congenital anomalies in the neonates, an increase in feeding difficulties and a reduced incidence of jaundice. There was no maternal or perinatal death. Refinements in management may further reduce the maternal and fetal morbidity in epileptic women who choose to become pregnant.
本文呈现了一项针对75名妊娠癫痫女性的回顾性研究，并与一组在产次、年龄和社会经济状况相匹配的女性对照组进行了比较。24%的女性在孕期癫痫控制情况恶化。在产科并发症方面，具有统计学意义的有贫血、早产、胎膜早破和产后出血。新生儿先天性异常的发生率增加了2.5倍，喂养困难增加，黄疸发生率降低。未发生孕产妇或围产期死亡。管理方法的改进可能会进一步降低选择怀孕的癫痫女性的孕产妇和胎儿发病率。
