[多肽分泌细胞高尔基体中网格蛋白的不对称分布]
[Asymmetrical distribution of clathrin in the Golgi apparatus of polypeptide-secreting cells].
作者信息
Orci L, Ravazzola M, Louvard D, Perrelet A
出版信息
C R Acad Sci III. 1984;299(17):697-702.
PMID:6440671
Abstract
Using an antibody revealed by the protein A-gold technique, we have studied the distribution of clathrin antigenic sites in the Golgi area of pancreatic B-cells. Golgi compartments showing an immunolabelling comprised extensive segments of cisternae, typical coated vesicles, dilated extremities of cisternae with condensing secretory material, and newly formed secretory granules. Most of the labelled membranes were observed at the trans Golgi pole while little immunoreactivity was found on the cis pole.
摘要
利用蛋白A-金技术揭示的一种抗体，我们研究了网格蛋白抗原位点在胰腺B细胞高尔基体区域的分布。显示免疫标记的高尔基体区室包括广泛的扁平囊泡片段、典型的有被小泡、含有浓缩分泌物质的扁平囊泡扩张末端，以及新形成的分泌颗粒。大多数标记的膜见于反式高尔基体极，而在顺式极几乎未发现免疫反应性。
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