Kurihara K, Ohba S, Hashimoto N
J Oral Pathol. 1984 Dec;13(6):679-85. doi: 10.1111/j.1600-0714.1984.tb01470.x.
A benign fibroblastic lesion simulating malignancy is reported. The lesion occurred in the right maxilla of an 11-year-old girl and perforated the outer cortical plate, suggesting malignancy. The biopsy, however, revealed proliferation of fibroblasts and fibrocytes with neither prominent atypia nor mitosis in a myxoid matrix. Electron microscopy showed that some fibroblastic cells were indeed myofibroblasts. As the lesion did not belong to any established entities, the final pathological diagnosis of benign fibroblastic lesion was made, leading to conservative surgery. The patient is well without recurrence 18 months after surgery.
报告了一例疑似恶性的良性成纤维细胞病变。该病变发生在一名11岁女孩的右上颌骨，穿破了外侧骨皮质板，提示为恶性。然而，活检显示成纤维细胞和纤维细胞增生，在黏液样基质中既无明显异型性也无核分裂象。电子显微镜检查显示一些成纤维细胞实际上是肌成纤维细胞。由于该病变不属于任何已确定的类型，最终病理诊断为良性成纤维细胞病变，随后进行了保守手术。患者术后18个月情况良好，无复发。
