类风湿性关节炎中侵蚀的影像学评估：金诺芬与安慰剂的双盲研究
Radiographic evaluation of erosion in rheumatoid arthritis: double blind study of auranofin vs placebo.
作者信息
Gofton J P, O'Brien W M, Hurley J N, Scheffler B J
出版信息
J Rheumatol. 1984 Dec;11(6):768-71.
PMID:6440982
Abstract
PA radiographs of hands and wrists from a randomized 6 month study of auranofin (AF) vs placebo followed by 6 months of open AF were scored for progression of erosive disease by 2 independent readers. The readers were blinded both to treatment and sequence (month 0 vs month 12) of the films. The results of our study demonstrate a reduction in the advancement of erosive disease during AF therapy compared to placebo.
摘要
在一项关于金诺芬（AF）与安慰剂的随机6个月研究中，对参与者双手和手腕的后前位X线片进行拍摄，随后进行6个月的金诺芬开放治疗，由2名独立阅片者对侵蚀性疾病的进展情况进行评分。阅片者对影片的治疗情况和顺序（第0个月与第12个月）均不知情。我们的研究结果表明，与安慰剂相比，金诺芬治疗期间侵蚀性疾病的进展有所减少。
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