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C-β-D-呋喃核糖基乙酸衍生物的合成及其在某些C-核苷合成中的应用。

Synthesis of C-beta-D-ribofuranosylacetic acid derivatives and their utilization in the synthesis of some C-nucleosides.

作者信息

Katagiri N, Haneda T, Takahashi N

出版信息

Nucleic Acids Symp Ser. 1984(15):37-40.

PMID:6441156
Abstract

Reactions of chloro(alkoxycarbonyl)methylenetriphenylphosphoranes with protected D-ribofuranoses resulted in the exclusive formation of C-beta-D-ribofuranosyl glycosides, which were converted to some C-nucleosides, such as showdomycin and pyrido-[1,2-a]pyrimidine C-nucleosides.

摘要

氯（烷氧羰基）亚甲基三苯基磷烷与受保护的D-呋喃核糖反应，专一性地生成β-D-呋喃核糖基糖苷，这些糖苷可转化为一些C-核苷，如showdomycin和吡啶并[1,2-a]嘧啶C-核苷。

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