Acquired pure megakaryocytic aplasia in course of hepatitis in a patient with immune thrombocytopenic purpura.

An unusual case of selective autoimmune myelopathy, a posthepatitic pure megakaryocytic aplasia, is reported. The disease manifested itself in a patient being treated for thrombocytopenic purpura caused by progressive administration of amitriptyline. The various clinical aspects of this unusual myelo-immunopathy seem to possess the same complexity and polymorphism of immune myelopathies.