Meoz R T, Hudgins P T, Wright A E
Rev Interam Radiol. 1978 Jan;3(1):15-9.
A group of patients treated with radiation therapy for bronchogenic carcinoma were evaluated with serial pulmonary function testing. The patients were treated with a split-course technique with 60-Cobalt. A total of 30 patients with unresectable carcinoma have been studied. Measurements of vital capacity (V.C.) and forced expiratory volume at one second (F.E.V.1) were made prior to therapy; at the beginning and end of the split; upon completion of therapy; and thereafter at 1, 2, and 6 months post therapy. The percentage changes in V.C. and F.E.V.1 from pretreatment values are plotted against time. A trend to improve throughout the treatment course is suggested by these results. Twelve patients have been studied at six-month follow-up: eight of the patients showed less than a 10% reduction from pretreatment V.C. and F.E.V.1 and had no respiratory impairment; of the other four patients, three had evidence of progression of disease in the thorax.
一组接受放射治疗的支气管源性癌患者通过系列肺功能测试进行评估。这些患者采用60钴的分段治疗技术。总共研究了30例不可切除癌患者。在治疗前、分段治疗开始和结束时、治疗完成时以及治疗后1、2和6个月测量肺活量（V.C.）和一秒用力呼气量（F.E.V.1）。将V.C.和F.E.V.1相对于治疗前值的百分比变化绘制成时间图。这些结果表明在整个治疗过程中有改善的趋势。对12例患者进行了为期6个月的随访研究：其中8例患者的V.C.和F.E.V.1较治疗前降低不到10%，且无呼吸功能损害；另外4例患者中，3例有胸部疾病进展的证据。
