Costa de Pasquale R, Ragusa S, Circosta C, Forestieri A M
J Ethnopharmacol. 1984 Dec;12(3):293-303. doi: 10.1016/0378-8741(84)90059-x.
Contraceptive activity and the correlated endocrine alterations of an aqueous extract of the leaves of Dieffenbachia amoena were investigated. In female Wistar rats the extract, given for 4 days during the estrous cycle, induced significant variations of luteinizing hormone (LH), follicle-stimulating hormone (FSH), prolactin (PRL) progesterone and 17 beta-estradiol levels. It also determined a reversible interruption of the estrous cycle with consequent temporary inhibition of ovulation.