Foca' A, Matera G, Chisari M, Mastroeni P, Caputi A P
G Batteriol Virol Immunol. 1984 Jan-Jun;77(1-6):9-18.
Endotoxins of Pasteurella multocida, Pseudomonas aeruginosa, Neisseria gonorrhoeae, and Shigella sonnei, when given in a single intravenous injection in the rat, showed antidipsogenic effects on drinking behaviour stimulated by 48 h water deprivation, or by intracerebroventricular injection of carbachol (250 ng). In water deprived rats, the antidipsogenic effect was dose related. When drinking was induced by carbachol, endotoxins showed a very long-lasting inhibition. The effect was neither a consequence of behavioural alterations, nor due endotoxin peripheral vasodilatating properties.
多杀巴斯德菌、铜绿假单胞菌、淋病奈瑟菌和宋内志贺菌的内毒素，当以单次静脉注射给予大鼠时，对因48小时禁水或脑室内注射卡巴胆碱（250纳克）刺激引起的饮水行为显示出抗渴作用。在禁水的大鼠中，抗渴作用与剂量相关。当由卡巴胆碱诱导饮水时，内毒素显示出非常持久的抑制作用。这种作用既不是行为改变的结果，也不是由于内毒素的外周血管舒张特性。
