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局部麻醉注射后出现的一种罕见皮肤反应。文献综述及4例报告

An unusual skin reaction following local anesthetic injection. Review of the literature and report of four cases.

作者信息

Lederman D A, Freedman P D, Kerpel S M, Lumerman H

出版信息

Oral Surg Oral Med Oral Pathol. 1980;49(1):28-33. doi: 10.1016/0030-4220(80)90028-6.

DOI:10.1016/0030-4220(80)90028-6
PMID:6444249
Abstract

Four cases of an unusual skin eruption related to mandibular block injection are presented. The authors suggest an immunologic basis for the reaction, probably to the methylparaben preseravtive, and discuss a possible pathogenic mechanism. The medical-dental literature concerning untoward reactions to lidocaine is reviewed; particular attention is given alleged allergic reactions.

摘要

本文报告了4例与下颌阻滞注射相关的罕见皮疹病例。作者认为该反应可能基于免疫机制,可能针对对羟基苯甲酸甲酯防腐剂,并探讨了可能的致病机制。对有关利多卡因不良反应的医学牙科文献进行了综述;特别关注了所谓的过敏反应。

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1
An unusual skin reaction following local anesthetic injection. Review of the literature and report of four cases.局部麻醉注射后出现的一种罕见皮肤反应。文献综述及4例报告
Oral Surg Oral Med Oral Pathol. 1980;49(1):28-33. doi: 10.1016/0030-4220(80)90028-6.
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Delayed-type hypersensitivity after subcutaneous administration of amide anesthetic.
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Petechial and purpuric eruption induced by lidocaine/prilocaine cream: a rare side effect.利多卡因/丙胺卡因乳膏引起的瘀点和紫癜疹:一种罕见的副作用。
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Type IV allergy to amide-type local anesthetics.对酰胺类局部麻醉药的IV型过敏反应。
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Allergic hypersensitivity to lidocaine hydrochloride.
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An unusual cutaneous reaction to lignocaine.对利多卡因的一种罕见皮肤反应。
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An allergic reaction following injection of local anesthetic: a case report.
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Immediate vesicular eruption caused by topical 23% lidocaine 7% tetracaine ointment in a patient scheduled for laser therapy: a new adverse drug reaction.患者拟行激光治疗,局部使用 23%利多卡因 7%丁卡因软膏后即刻出现水疱性皮疹:一种新的药物不良反应。
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引用本文的文献

1
Place of excipients in drug-related allergy.辅料在药物相关过敏中的作用。
Clin Rev Allergy Immunol. 1995 Fall;13(3):253-63. doi: 10.1007/BF02771765.
2
Evaluation and management of hypersensitivity to local anesthetics in pediatric dentistry.儿童牙科中局部麻醉药过敏的评估与管理
Anesth Prog. 1987 Sep-Oct;34(5):191-4.
3
A guideline to local anesthetic allergy testing.局部麻醉过敏试验指南。
Anesth Prog. 1987 Sep-Oct;34(5):157-63.
4
Pharmaceutical excipients. Adverse effects associated with 'inactive' ingredients in drug products (Part II).药用辅料。药品中与“非活性”成分相关的不良反应(第二部分)。
Med Toxicol Adverse Drug Exp. 1988 May-Jun;3(3):209-40. doi: 10.1007/BF03259883.