Shiu M H, Flancbaum L, Hajdu S I, Fortner J G
Arch Surg. 1980 Feb;115(2):152-5. doi: 10.1001/archsurg.1980.01380020020005.
A clinicopathologic study was made of 32 soft-tissue sarcomas of the anterior abdominal wall (ten desmoid tumors and 22 fully malignant sarcomas). Direct invasion of the costal margin or the iliac crest was observed in both types, whereas transperitoneal invasion and metastasis developed characteristically with fully malignant sarcomas. Wide monobloc resection of the abdominal wall, including, where necessary, resection of adjacent bony parts and reconstruction with a prosthetic mesh, satisfactorily controlled local disease in nine of ten patients with desmoid tumor, and in three of four patients with primary operable, fully malignant sarcoma. Adjunctive therapy with radiation and chemotherapy may improve the outcome in patients with recurrent or high-grade sarcomas, but adequate monobloc resection of the primary tumor remains the most important therapeutic objective.
对32例腹壁软组织肉瘤（10例硬纤维瘤和22例完全恶性肉瘤）进行了临床病理研究。在这两种类型中均观察到肋缘或髂嵴的直接侵犯，而经腹膜侵犯和转移则是完全恶性肉瘤的典型特征。对腹壁进行广泛整块切除，必要时包括切除相邻的骨质部分并用人工网片进行重建，10例硬纤维瘤患者中有9例、4例原发性可手术完全恶性肉瘤患者中有3例的局部疾病得到了满意控制。放疗和化疗等辅助治疗可能会改善复发或高级别肉瘤患者的预后，但对原发性肿瘤进行充分的整块切除仍然是最重要的治疗目标。
