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维生素C预防铬性皮炎。

Ascorbic acid in the prevention of chromium dermatitis.

作者信息

Milner J E

出版信息

J Occup Med. 1980 Jan;22(1):51-2.

PMID:6444442
Abstract

A worker with strong chromium sensitivity was obliged to handle freshly printed paper with inks containing chromium. Because of his importance to the firm, he continued in the position despite a severe hand dermatitis. Gloves and barrier creams were unacceptable, as were oral antihistamines and corticosteroids. A solution of 10% ascorbic acid was applied to his hands at the worksite in order to reduce the active hexavalent chromium to the inactive trivalent form. This inexpensive, easy-to-use method resulted in a speedy recovery and long-term employment of a valued employee.

摘要

一名对铬高度敏感的工人不得不处理含有铬的油墨刚印好的纸张。由于他对公司很重要,尽管手部患有严重的皮炎,他仍继续留在该岗位。手套和防护霜都不可用,口服抗组胺药和皮质类固醇也不行。为了将活性六价铬还原为无活性的三价形式,在工作现场给他的手上涂抹了10%的抗坏血酸溶液。这种廉价且易于使用的方法使一位重要员工迅速康复并得以长期留用。

相似文献

1
Ascorbic acid in the prevention of chromium dermatitis.维生素C预防铬性皮炎。
J Occup Med. 1980 Jan;22(1):51-2.
2
[Chemical inactivation method and its role in the prevention of occupational allergic dermatoses].[化学灭活方法及其在预防职业性过敏性皮肤病中的作用]
Vestn Dermatol Venerol. 1976 Aug(8):81-4.
3
[Early diagnosis and effective prevention of occupational allergies caused by hexavalent chromium].[六价铬所致职业性过敏的早期诊断与有效预防]
Med Tr Prom Ekol. 1995(11):34-7.
4
[Prophylaxis of patients with sensitization to chrome and nickel using a cosmetic preparation for topical use].[使用一种局部用化妆品制剂对铬和镍致敏患者进行预防]
Med Cutan Ibero Lat Am. 1983;11(2):139-46.
5
Hexavalent chromium in leather is now regulated in European Union member states to limit chromium allergy and dermatitis.欧盟成员国现已对皮革中的六价铬进行管控,以限制铬过敏和皮炎。
Contact Dermatitis. 2014 Jan;70(1):1-2. doi: 10.1111/cod.12182.
6
Exposure to chromium from hospital cleaning.医院清洁过程中接触铬。
Derm Beruf Umwelt. 1983;31(2):54-7.
7
Effect of hand dermatitis on the total body burden of chromium after ferrous sulfate application in cement among cement workers.手部皮炎对水泥工应用硫酸亚铁后体内铬总负荷的影响
Contact Dermatitis. 2008 Sep;59(3):151-6. doi: 10.1111/j.1600-0536.2008.01403.x.
8
Therapeutic review: is ascorbic acid of value in chromium poisoning and chromium dermatitis?治疗综述:抗坏血酸对铬中毒和铬性皮炎有价值吗?
J Toxicol Clin Toxicol. 1999;37(2):195-200. doi: 10.1081/clt-100102419.
9
Do barrier creams and gloves prevent or provoke contact dermatitis?屏障乳膏和手套能预防还是引发接触性皮炎?
Am J Contact Dermat. 1998 Jun;9(2):100-6.
10
Trivalent chromium plating.三价铬电镀
Contact Dermatitis. 1980 Apr;6(3):222. doi: 10.1111/j.1600-0536.1980.tb05609.x.

引用本文的文献

1
Experimental bases for ascorbic acid therapy of poisoning by hexavalent chromium compounds.六价铬化合物中毒的抗坏血酸疗法的实验依据。
Int Arch Occup Environ Health. 1984;53(3):247-56. doi: 10.1007/BF00398817.
2
Reduction of hexavalent chromium by ascorbic acid in rat lung lavage fluid.抗坏血酸对大鼠肺灌洗液中六价铬的还原作用。
Arch Toxicol. 1988;62(2-3):116-22. doi: 10.1007/BF00570129.