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影响供体人工授精成功率的因素。

Factors affecting donor artificial insemination success rates.

作者信息

Corson S L

出版信息

Fertil Steril. 1980 Apr;33(4):415-22.

PMID:6444898
Abstract

Pregnancy was achieved at least once by 75 of 100 women treated with artificial insemination donor (AID). In all, 94 gestations were recorded, with a mean time to achieve pregnancy of 3.3 cycles. Success rates were studied relative to ovulatory function, cervical mucus parameters, previous reproductive history, and following pelvic surgery. A life-table analysis of conception according to actual inseminations performed during each cycle gave a 61% conception rate within 6 months, including patients who discontinued therapy after only one treatment cycle. Clomiphene citrate was used freely for ovulation induction. These patients took longer to conceive (5.5 cycles), but had an abortion rate similar to that of the general group. An effect of cervical mucus on the time necessary to initiate pregnancy was not demonstrated. Six of seven patients who had undergone reparative surgery for restoration or promotion of fertility conceived. The highest number of conceptions with double AID was found on cycle days 13 and 15.

摘要

接受供体人工授精(AID)治疗的100名女性中,至少有75人成功怀孕过一次。总共记录到94次妊娠,平均受孕时间为3.3个周期。研究了成功率与排卵功能、宫颈黏液参数、既往生育史以及盆腔手术后情况的关系。根据每个周期实际进行的授精情况进行的受孕生命表分析显示,6个月内的受孕率为61%,包括仅接受一个治疗周期后就停止治疗的患者。枸橼酸氯米芬可自由用于诱导排卵。这些患者受孕时间较长(5.5个周期),但流产率与普通组相似。未证实宫颈黏液对开始妊娠所需时间有影响。接受过恢复或促进生育的修复手术的7名患者中有6人怀孕。双次AID受孕最多的时间是在周期的第13天和第15天。

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