Staricco R G
Dermatologica. 1980;160(5):315-20. doi: 10.1159/000250512.
66 psoriatics, 34 normal adults, 10 normal juveniles, and smaller groups of patients afflicted either with seborrheic dermatitis-rosacea or atopic dermatitis were examined for the threshold of capillary petechia formation on clinically normal forearm skin in response to repeated tape stripping. A definitely lowered petechial threshold was found in psoriatics (mean of 9 vs. 19 tape strips) and also in persons with the seborrheic-rosacea complex. Normal juveniles and patients with atopic dermatitis had an increased threshold. The possible relation of these data are pointed out to recent findings of ultrastructural abnormalities of psoriatic papillary capillaries, and an altered capillary response is suggested as a sine qua non precondition for the development of psoriasis. The petechial threshold test is recommended as a simple adjunct diagnostic tool.
对66名银屑病患者、34名正常成年人、10名正常青少年以及少量患有脂溢性皮炎 - 酒渣鼻或特应性皮炎的患者,检测其临床正常的前臂皮肤在反复胶带剥离后形成毛细血管瘀点的阈值。结果发现,银屑病患者(平均9次胶带剥离 vs. 19次胶带剥离)以及患有脂溢性皮炎 - 酒渣鼻综合征的人群的瘀点阈值明显降低。正常青少年和特应性皮炎患者的阈值升高。文中指出了这些数据与银屑病乳头毛细血管超微结构异常的最新发现之间可能存在的关系,并提出毛细血管反应改变是银屑病发生的必要前提条件。建议将瘀点阈值测试作为一种简单的辅助诊断工具。