三氟拉嗪对平滑肌肌动球蛋白的作用。简短通讯。
Effects of trifluoperazine on smooth muscle actomyosin. Short communication.
作者信息
Mrwa U, Peterson J W, Rüegg J C
出版信息
Arzneimittelforschung. 1980;30(1):114-6.
PMID:6445196
Abstract
Trifluoperazine (TFP) inhibits superprecipitation and ATPase activity of smooth muscle actomyosin. This effect appears not to be due to the inhibitory effect of TFP on the Ca++-dependent modulator and the myosin light chain kinase, which are known to be cofactors required for activation of smooth muscle actomyosin.
摘要
三氟拉嗪（TFP）可抑制平滑肌肌动球蛋白的超沉淀和ATP酶活性。这种作用似乎并非由于TFP对钙离子依赖性调节蛋白和肌球蛋白轻链激酶的抑制作用，而这两种蛋白已知是激活平滑肌肌动球蛋白所需的辅助因子。
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