Acid phosphatase activity of RHS in rats stimulated with pneumococci suspensions by respiratory and intramuscular ways.

Young albino rats stimulated by respiratory and parenteral ways with living pneumococci and respectively emulsion of killed germs in complete Freund adjuvant present an enhanced acid phosphatase activity of histiocytes in lung, liver, spleen and lymph nodes, correlated with hyperplasia of the intensely reactive cells, signifying an increased phagocytic capacity of RHS. The difference between the experimental groups, mainly quantitative, are conditioned by the nature of the antigenic material.