Goffin Y, de Doncker E
Rev Rhum Mal Osteoartic. 1980 Jan;47(1):15-20.
The authors make a histological and histochemical study of the articular capsule, in arthrosis and senescence. They basically observe fibrosis and a decrease of the elastic tissue in aged subjects and an increase in the level of acid mucopolysaccharides of the interstitial in more than 50% of arthrosics. There are also micro-deposits of amyloid substances in more than 25% of subjects over eighty. This study provides an argument in favor of the opinion of Lagier according to which arthrosis should not be considered the same as a manifestation of senescence. On the other hand, it appears that microscopic amyloidose of the articular capsule of the old patient is not related to arthrosic phenomena but rather constitutes a local manifestation of senescence.
作者对患有关节炎和处于衰老状态的关节囊进行了组织学和组织化学研究。他们基本观察到，老年受试者的关节囊存在纤维化且弹性组织减少，超过50%的关节炎患者间质酸性粘多糖水平升高。在80岁以上的受试者中，超过25%还存在淀粉样物质的微沉积。这项研究为拉吉尔的观点提供了论据，即不应将关节炎视为衰老的一种表现。另一方面，老年患者关节囊的微观淀粉样变似乎与关节炎现象无关，而更像是衰老的一种局部表现。
