Stadalnik R C, Goldstein E, Hoeprich P D, dos Santos P A, Lee K K
Am Rev Respir Dis. 1980 Apr;121(4):673-6. doi: 10.1164/arrd.1980.121.4.673.
The value of 67Ga and methylene diphosphonate labeled with 99mTc in detecting extrapulmonary lesions was evaluated in 12 patients win whom disseminated nonmeningeal coccidioidomycosis developed after a single epidemic exposure in December 1977. Studies were performed with each radionuclide from 4 to 9 months after infection. Comparison of scintigraphy with radiography showed that eight of 14 osteolytic lesions identified by radiography were present on the bone and gallium scans; four were present only on the gallium scan, and two were undetected. Of 15 additional lesions present in both scanning procedures, eight were not present in matching roentgenograms and seven were in unstudied areas. Gallium scans detected seven of 14 soft tissue lesions. Few diagnostically confusing noninfectious lesions were observed. Because nuclear scanning detected almost all lesions present in radiographs and demonstrated otherwise unrecognized lesions, scans should be performed in all patients in whom coccidioidal dissemination is suspected.
对12例于1977年12月单次流行暴露后发生播散性非脑膜球孢子菌病的患者，评估了67镓和99m锝标记的亚甲基二膦酸盐在检测肺外病变中的价值。在感染后4至9个月用每种放射性核素进行研究。闪烁扫描与X线摄影的比较显示，X线摄影确定的14个溶骨性病变中有8个在骨扫描和镓扫描中显示；4个仅在镓扫描中显示，2个未被检测到。在两种扫描程序中均存在的另外15个病变中，8个在匹配的X线片中未显示，7个在未研究区域。镓扫描检测到14个软组织病变中的7个。观察到很少有诊断混淆的非感染性病变。由于核扫描检测到了X线片中几乎所有存在的病变，并显示了其他未被识别的病变，因此对于所有疑似球孢子菌播散的患者都应进行扫描。
