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[白鼠在适应不同类型体力负荷过程中心脏形态学改变的差异]

[Variations in morphologic alterations in the hearts of white rats during adaptation to different types of physical loads].

作者信息

Pinchuk V M, Frolov B A

出版信息

Arkh Anat Gistol Embriol. 1980 Feb;78(2):30-6.

PMID:6446273
Abstract

While adapting to physical loadings various in their character, most of rats develop a moderate hypertrophy in the right cardiac ventricle without any noticeable changes in the organ's mass. ECG dynamics is positive. Myocardial hypertrophy, at the expense of increasing mass of the left ventricle, is most regularly observed in animals subjected to forced endurance training (daily swimming); less regularly--if the loading is applied with intervals (swimming every other day) and is practically absent in rats performing work with force application. Pathological ECG changes occur more often on the background of myocardial hypertrophy and are brought about by dystrophic disorders in muscular fibres, their focal micronecrosis, by edema of the interstitial and perivascular tissue.

摘要

在适应各种不同性质的体力负荷时,大多数大鼠右心室出现中度肥大,而器官质量无明显变化。心电图动态呈阳性。以左心室质量增加为代价的心肌肥大,最常出现在接受强迫耐力训练(每日游泳)的动物身上;不太常见——如果负荷是间歇性施加的(隔天游泳),而在进行用力工作的大鼠中几乎不存在。病理性心电图变化更常出现在心肌肥大的背景下,是由肌纤维的营养不良性病变、局灶性微坏死以及间质和血管周围组织水肿引起的。

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