Cheng T H, Holman B L
Radiology. 1980 Aug;136(2):455-9. doi: 10.1148/radiology.136.2.6447313.
Twenty-four patients with increased skeletal:renal uptake ratios of 99mTc-methylene diphosphonate were studied. Increased uptake was central in metastatic prostate carcinoma, peripheral in hematologic disorders, and heterogeneous in Paget disease and fibrous dysplasia. There was no discernible redistribution of skeletal uptake in patients with renal failure. Absence of both renal and bladder activity was not observed in patients with normal renal function. An increased ratio was always abnormal and frequently indicated diffuse bone disease.
对24例99m锝-亚甲基二膦酸盐骨骼：肾脏摄取率升高的患者进行了研究。摄取增加在转移性前列腺癌中为中央型，在血液系统疾病中为外周型，在佩吉特病和骨纤维发育不良中为不均匀型。肾衰竭患者的骨骼摄取未见明显再分布。肾功能正常的患者未观察到肾脏和膀胱均无放射性活性的情况。摄取率升高总是异常的，且常提示弥漫性骨病。
