[Trigger mechanisms in the etiology of varicose and post-thrombophlebitic crural ulcers].

The results of clinical study of 247 cases suffering from trophic crural ulcer are set forth in this paper. Their occurrence is mainly due to various diseases of deep, communicant and superficial veins (236 cases 95%). Venous hypertension in the deep veins, while the patient is standing, is the leading cause of the microcirculation disorders, occurrence of interstitial edema, and opening of arterio-venous shunts. Tissue hypoxia and an infection, arising against this background, lead to the expansion of necrobiosis and to the occurrence of trophic ulcers. The therapeutic principles grounded upon the results of the presented study are brought about in this work.