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[用锂替代细胞外钠对由戊四氮和士的宁这两种惊厥剂引起的非洲大蜗牛可识别巨型神经元异常锋电位发放的不同影响]

[Different effects of the replacement of extracellular sodium with lithium on the abnormal spike discharges caused by 2 convulsants, Metrazol and strychnine, on an identifiable giant neuron of the mollusc Achatina fulica Ferussac].

作者信息

Miyamoto M, Tamura H, Takeuchi H, Endo I

出版信息

C R Seances Soc Biol Fil. 1980;174(3):285-9.

PMID:6448671
Abstract

The influences of the replacement of sodium with lithium in the extracellular medium on the abnormal spike discharges, caused by two convulsants, metrazol and strychnine, of a giant neurone (TAN, tonically autoactive neurone) identified in the suboesophageal ganglia of the African giant snail (Achatina fulica Férussac) were examined. The slow oscillations of potential caused by metrazol disappeared after this replacement. On the other hand, the abnormal action potentials caused by strychnine, as well as the normal action potentials, still remained after the removal of sodium in the medium.

摘要

研究了在非洲大蜗牛(Achatina fulica Férussac)食管下神经节中鉴定出的一种巨型神经元(TAN,紧张性自发放电神经元)的细胞外介质中用锂替代钠对由两种惊厥剂戊四氮和士的宁引起的异常尖峰放电的影响。戊四氮引起的电位缓慢振荡在这种替代后消失。另一方面,士的宁引起的异常动作电位以及正常动作电位在介质中去除钠后仍然存在。

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1
[Different effects of the replacement of extracellular sodium with lithium on the abnormal spike discharges caused by 2 convulsants, Metrazol and strychnine, on an identifiable giant neuron of the mollusc Achatina fulica Ferussac].[用锂替代细胞外钠对由戊四氮和士的宁这两种惊厥剂引起的非洲大蜗牛可识别巨型神经元异常锋电位发放的不同影响]
C R Seances Soc Biol Fil. 1980;174(3):285-9.
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