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人工流产对夏威夷唐氏综合征发病率的影响。

The effect of induced abortion on the incidence of Down's syndrome in Hawaii.

作者信息

Smith R G, Gardner R W, Steinhoff P, Chung C S, Palmore J A

出版信息

Fam Plann Perspect. 1980 Jul-Aug;12(4):201-5.

PMID:6449372
Abstract

There was a decrease in the recorded number of cases and in the incidence rate of Down's syndrome in Hawaii between 1963-1969 and 1971-1977. Independent of all other factors, induced abortion accounted for 43 percent of the decline in the number of cases, based on the assumption that a substantial number of clandestine abortions were being performed in Hawaii before the 1970 legalization of abortion. However, if we assume that very few illegal abortions were performed prior to 1970, there would have been an actual 3.5 percent increase in the number of cases of Down's syndrome in the absence of legal abortion. Declining pregnancy rates and decreasing age-specific incidence rates of Down's syndrome also contributed to the drop in the number of cases between 1963-1969 and 1971-1977.

摘要

1963年至1969年以及1971年至1977年期间,夏威夷记录的唐氏综合征病例数和发病率有所下降。在不考虑所有其他因素的情况下,基于1970年堕胎合法化之前夏威夷进行了大量秘密堕胎这一假设,人工流产占病例数下降的43%。然而,如果我们假设1970年之前进行的非法堕胎极少,那么在没有合法堕胎的情况下,唐氏综合征病例数实际上会增加3.5%。妊娠率下降以及唐氏综合征特定年龄发病率下降也导致了1963年至1969年以及1971年至1977年期间病例数的减少。

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