[不同远距照射方案下宫颈癌细胞的有丝分裂活性]
[Mitotic activity of cervical cancer cells under different teleirradiation regimens].
作者信息
Gubareva A V, Markochev A B, Rossol'ko S D, Gabelov A A, Zharinov G M
出版信息
Vopr Onkol. 1978;24(3):21-5.
Radiation pathomorphosis of cervical cancer stage I-II was estimated quantitatively in a comparative aspect under 4 different regimens of distance split-course irradiation, being the first step of an associated radiotherapy. Irradiation (using the Luch-1 machine) consisted of two two-week steps with an interval of 14-21 days. Tumor foci were given a total of 1800 rad during each step. An efficacy of radiation exposure in daily irradiation (180 radx5) was lowered as compared with an average fractionation (450 radx2). Fractionation of a daily dosage (225 radx2 with an interval of 5-6 hours and 150 radx3 with a 3 hour interval) was followed by less effect of radiation exposure, mostly manifest in triple fractionation of a daily dosage.
在联合放疗的第一步，对4种不同的远距离分割放疗方案下I-II期宫颈癌的放射病理形态变化进行了定量比较评估。照射（使用Luch-1机器）包括两个为期两周的阶段，间隔14 - 21天。每个阶段肿瘤病灶接受的总辐射剂量为1800拉德。与平均分割（450拉德×2）相比，每日照射（180拉德×5）的辐射暴露效果降低。每日剂量分割（225拉德×2，间隔5 - 6小时，以及150拉德×3，间隔3小时）后辐射暴露效果更差，主要体现在每日剂量的三次分割上。
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