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[阿塞拜疆GPD - 等位基因分布模式。II. 舍基区3个村庄的群体遗传结构]

[Patterns in the distribution of GPD- alleles in Azerbaijan. II. Population genetic structure of 3 villages in the Shekii district].

作者信息

Krasnopol'skaia K D, Filippov I K, Sotnikova E N, Movsum-Zade K M, Gadzhiev B O

出版信息

Genetika. 1980;16(9):1693-1700.

PMID:6450086
Abstract

In order to clear out the role of genetico-automatic processes in Gd- distribution the investigation of population structure of three settlements in the Shekii district was carried out. Sex and age ratios and the average number of living children on one marriage (> 5.7) bear evidence of expanded reproduction in this population. The high frequency of endogamous marriages (approximately 80%) and 14 cases of consaguinous marriage for 183 analysed pedigree were revealed. The allele frequencies in 6 polymorphic systems were determined: ABO, Rh, Hp, PGM, Gc and AP; in the first three there were found out the statistically significant differences in alleles' frequency between subpopulations, but not in the last three systems. The differentiation type of allele frequency in all 6 loci was similar in subpopulations. The inbreeding coefficient fst determined upon the differentiation of the gene frequency at three loci is 0.00583.

摘要

为了弄清楚遗传自动过程在钆分布中的作用,对舍基地区三个定居点的人口结构进行了调查。性别和年龄比例以及每桩婚姻(>5.7)的平均存活子女数证明了该人群繁殖率的提高。研究发现近亲结婚的频率很高(约80%),在183个分析家系中有14例近亲婚姻。测定了6个多态系统中的等位基因频率:ABO、Rh、Hp、PGM、Gc和AP;在前三个系统中,发现亚群之间等位基因频率存在统计学显著差异,而后三个系统则没有。所有6个位点的等位基因频率分化类型在亚群中相似。根据三个位点基因频率的分化确定的近交系数fst为0.00583。

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