Vita G F, Mastaglia F L
Neuropathol Appl Neurobiol. 1980 Nov-Dec;6(6):465-70. doi: 10.1111/j.1365-2990.1980.tb00223.x.
The effects of thyroidectomy on the metabolic properties of the rat extraocular muscles have been studied using histochemical techniques. Six months after removal of the thyroid gland a significant increase in the proportion of Type 1 fibres was found in the central zone of the superior rectus (SR) and in the levator palpebrae superioris muscles. Other changes included an increased proportion of Type 2a' fibres and reduced proportions of Type 2a and 2b fibres in the central zone of the SR, and an increased proportion of type 2a, and a reduced proportion of Type 2a" fibres in the peripheral zone of the SR, Mr and So. In addition, there was a mild hypertrophy of Type 1 fibres in the MR, and a mild atrophy of Type 2 fibres in each of the muscles studies. The physiological significance of these findings is discussed.
已使用组织化学技术研究了甲状腺切除术对大鼠眼外肌代谢特性的影响。甲状腺切除六个月后，在上直肌（SR）中央区域和上睑提肌中发现1型纤维比例显著增加。其他变化包括：SR中央区域2a'纤维比例增加，2a和2b纤维比例降低；SR、内直肌（MR）和下斜肌（So）外周区域2a纤维比例增加，2a"纤维比例降低。此外，MR中1型纤维有轻度肥大，在所研究的每块肌肉中2型纤维有轻度萎缩。讨论了这些发现的生理学意义。
