Abronina I F, Karaulov A V, Brondz B D
Biull Eksp Biol Med. 1980 Dec;90(12):703-5.
Intravenous immunization of mice with a large dose of gamma-irradiated allogenic spleen cells gives rise to specific suppressor T cells and cytotoxic lymphocytes (CTL). However, being optimal form suppressor T cell induction, these conditions of immunization are not conducive to identification of CTL unless they are enriched by elution from the allogenic target monolayer. Unlike CTL, specific suppressor T cells are highly susceptible to gamma-irradiation while their precursors differ from those of CTL by high susceptibility to cyclophosphamide and hydrocortisone.
用大剂量经γ射线照射的同种异体脾细胞对小鼠进行静脉免疫，可产生特异性抑制性T细胞和细胞毒性淋巴细胞（CTL）。然而，作为诱导抑制性T细胞的最佳形式，这些免疫条件不利于CTL的鉴定，除非通过从同种异体靶单层洗脱来富集它们。与CTL不同，特异性抑制性T细胞对γ射线高度敏感，而它们的前体细胞与CTL的前体细胞不同，对环磷酰胺和氢化可的松高度敏感。
