Hannouche N, Samperez S, Jouan P
C R Seances Soc Biol Fil. 1980;174(6):963-8.
The lack of 5 alpha-reductase activity in purified membranes of hypothalamic cells or in myelin was demonstrated. On the other hand, it was shown that incubation of hypothalamic slices with tritiated testosterone resulted in the accumulation and retention of 5 alpha-dihydrotestosterone in purified plasmic membranes and in myelin. The biological significance of such a retention remains unknown.
已证实在下丘脑细胞的纯化膜或髓磷脂中缺乏5α-还原酶活性。另一方面，研究表明，用氚标记的睾酮孵育下丘脑切片会导致5α-二氢睾酮在纯化的质膜和髓磷脂中积累和保留。这种保留的生物学意义尚不清楚。
