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[强直性肌营养不良(库尔施曼-施泰纳特病)中的交替性心电图改变]

[Alternating ECG changes in dystrophia myotonica (Curschmann-Steinert)].

作者信息

Wagner A, Graf B, Hohlfeld R, Trenckmann H

出版信息

Z Gesamte Inn Med. 1978 Feb 15;33(4):105-9.

PMID:645140
Abstract

It is reported on a 39-year-old patient who revealed pathological ECG-findings of the most different kind during several years. Since there were no clues to a myocarditis, later on, however, pareses of atrophical skeletal muscles developed and a distropia myotonica could be diagnosed, the cardiological disturbances are to be regarded as a symptom of this disease. When also a participation of the myocardium in the distrophia myotonica is not unknown, so even in our case the frequently changing disturbances of the nervous impulses of the heart, of the ventricular stimulus conduction and of the replolarisation of different expression as well as the pronounced hypersensitivity to heart glycosides are remarkable individual findings. The interpretation of these findings is problematic. Morphologic and dystrophic changes of the myocardium as well as functional myotonic disturbances on the membraneous system may influence the process of stimulation and may cause the clinical appearances.

摘要

据报道,一名39岁患者在数年中出现了各种不同的病理性心电图表现。由于没有心肌炎的线索,但后来出现了萎缩性骨骼肌麻痹,并诊断为强直性肌营养不良症,因此心脏方面的紊乱应被视为该疾病的一种症状。当心肌也参与强直性肌营养不良症并不罕见时,所以即使在我们的病例中,心脏神经冲动、心室刺激传导以及不同表现的复极化频繁变化的紊乱,以及对强心苷的明显高敏反应都是显著的个体表现。这些表现的解释存在问题。心肌的形态学和营养不良性变化以及膜系统上的功能性肌强直紊乱可能会影响刺激过程,并可能导致临床表现。

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