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[犬和小型猪封闭胸腔内直流电诱导实验性冠状动脉血栓形成时的心电图与血流动力学]

[ECG and hemodynamics in experimental coronary thrombosis induced by direct current in the closed thorax of the dog and mini-pig].

作者信息

Sedlarik K, Fiehring H, Schilling B, Wilde J

出版信息

Z Exp Chir. 1978;11(1):52-8.

PMID:645160
Abstract

Coronary thrombosis is a life-threatening disease that, as a rule, leads to myocardial infarction. The onset and the course of this disease are followed in animal experiments with the aid of electrocardiograms and some haemodynamic parameters. There was a biphasic course, i.e., the authors observed first a rise and then a striking drop in peripheral arterial pressure and a rise in central venous pressure. The electrocardiograms and blood-pressure controls evidenced that the induction of coronary thrombosis is more difficult in the minipig than in the dog.

摘要

冠状动脉血栓形成是一种危及生命的疾病,通常会导致心肌梗死。在动物实验中借助心电图和一些血流动力学参数来跟踪这种疾病的发作和病程。其病程呈双相性,即作者首先观察到外周动脉压先升高然后显著下降,以及中心静脉压升高。心电图和血压监测表明,小型猪诱发冠状动脉血栓形成比狗更困难。

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