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头孢哌酮在儿科领域的临床研究(作者译)

[Clinical studies of cefoperazone in pediatric field (author's transl)].

作者信息

Aoyama R, Kuronuma T, Nagata K, Izumi Y

出版信息

Jpn J Antibiot. 1980 Aug;33(8):799-802.

PMID:6451727
Abstract

Clinical studies of cefoperazone (CPZ) were performed and the following results were obtained. 1) CPZ was intravenously administered at the daily dose of 35 approximately 107 mg/kg to 10 children with infection: urinary tract infection (6 cases), respiratory infection (3 cases), and acute enterocolitis (1 case). The overall efficacy rate was 80%, and in urinary tract infection including one case caused by Pseudomonas aeruginosa, efficacy rate was 100%. 2) The bloody stools were noted in one case, 2 days after the administration of CPZ, but improved gradually. No abnormal laboratory data were found.

摘要

进行了头孢哌酮(CPZ)的临床研究,并获得了以下结果。1)对10名感染儿童静脉注射CPZ,日剂量约为35至107mg/kg,感染类型包括:尿路感染(6例)、呼吸道感染(3例)和急性小肠结肠炎(1例)。总有效率为80%,在包括1例由铜绿假单胞菌引起的尿路感染中,有效率为100%。2)1例患者在使用CPZ后2天出现血便,但逐渐好转。未发现实验室数据异常。

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