Serum inorganic phosphate and serum calcium in middle-aged men. II. Relation to glucose and insulin parameters in glucose tolerance tests.

Fasting serum inorganic phosphate and fasting serum calcium were measured in 752 49-year-old Malmö males, in whom an oral or i.v. glucose tolerance test, in 189 cases including plasma insulin measurements, was performed as part of an internal medical screening examination. The serum inorganic phosphate and calcium levels were analysed statistically in relation to various glucose and insulin response parameters. A significant, positive correlation of serum inorganic phosphate with the early insulin response in the i.v. glucose tolerance tests was found but not with any of the other glucose or insulin response parameters included in the study. Serum calcium showed no significant correlations. These findings are discussed in relation to the pertinent literature.