同源人工授精

Homologous artificial insemination.

作者信息

Corson S L, Batzer F F

出版信息

J Reprod Med. 1981 May;26(5):231-42.

Abstract

Artificial insemination--homologous (AIH) treatment in 100 couples is presented. An uncorrected pregnancy rate of 13% was achieved therapeutically versus a 10% spontaneous pregnancy rate. An adjusted pregnancy rate for those who conceived or completed at least six cycles of treatment was 41%. A pregnancy rate of 8% was obtained in 25 cases of oligospermia (less than 20 X 10(6)/ml), 15% in 27 cases of decreased motility only (less than 45% active), 27% in 18 cases of unexplained poor postcoital tests and 28% in 18 couples with suspected or proven immunologic problems. The most important reason for lack of success in our series appeared to be failure to continue therapy for an adequate period, defined as a minimum of six cycles. Since indications for AIH are less well defined than for artificial insemination with donor (AID), pregnancy yields are less reliable as an indication of a causal relationship.

摘要

本文介绍了对100对夫妇进行的同种人工授精（AIH）治疗。治疗性未校正妊娠率为13%，而自然妊娠率为10%。对于那些受孕或完成至少六个治疗周期的患者，校正后的妊娠率为41%。25例少精子症（少于20×10⁶/ml）患者的妊娠率为8%，27例仅活力下降（活性少于45%）患者的妊娠率为15%，18例不明原因性交后试验不佳患者的妊娠率为27%，18对怀疑或证实有免疫问题的夫妇的妊娠率为28%。在我们的系列研究中，治疗未成功的最重要原因似乎是未能持续足够长的治疗时间，定义为至少六个周期。由于AIH的适应症不如供体人工授精（AID）明确，妊娠结果作为因果关系的指标不太可靠。