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通过吸入131-碘化甲烷成像检测实验性产生的急性肺动脉闭塞

Detection of experimentally produced acute pulmonary arterial occlusion by methyl iodide-131 inhalation imaging.

作者信息

Grossman Z D, McAfee J G, Subramanian G, Ritter C A, Thomas F D, Lyons B J, Gagne G M, Zens A, Farrar F, Feld T, Fernandes P, Johnson A C

出版信息

Radiology. 1981 Aug;140(2):499-503. doi: 10.1148/radiology.140.2.6454902.

DOI:10.1148/radiology.140.2.6454902
PMID:6454902
Abstract

Methyl iodide-131 (CH3I-131) is described as an agent for detection of acute experimentally produced pulmonary arterial occlusion in dogs. When gaseous CH3I-131 is inhaled, radioactivity passes instantaneously from the alveoli to the lung capillary bed. Where pulmonary blood flow exists, activity is washed out into the systemic circulation, but in areas of blood stasis, a transient pulmonary "hot spot" remains. CH3I-131 is easily produced and inexpensive, but administration is awkward and strict radiation safety precautions are mandatory.

摘要

碘化甲基-131(CH3I-131)被描述为一种用于检测犬类实验性急性肺动脉闭塞的试剂。当吸入气态CH3I-131时,放射性物质会瞬间从肺泡进入肺毛细血管床。在有肺血流的地方,活性物质会被冲刷到体循环中,但在血流淤滞的区域,会留下一个短暂的肺部“热点”。CH3I-131易于制备且价格低廉,但给药操作不便,必须采取严格的辐射安全预防措施。

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