Moretti G, Manzoni G C, Caffarra P, Ceccato S
Acta Biomed Ateneo Parmense. 1981;52(1):25-9.
The Authors report the case of a 32-years-old woman taking oral contraceptives for twelve years, who developed multi-infarct dementia and motor-sensory signs as a consequence of repeated cerebrovascular episodes associated with migraine-like attacks. Neuroradiological findings suggested vascular pathologic changes. Mechanisms of cerebro-vascular diseases related to oral contraception are discussed, especially emphasizing the possibility of intrinsic vascular lesions caused by exogenous steroid stimulation. Epidemiologic and pathophysiological relationship between migraine, stroke and oral contraception are also pointed out.
作者报告了一例32岁女性的病例,该女性服用口服避孕药12年,因与偏头痛样发作相关的反复脑血管事件而发展为多发性梗死性痴呆和运动感觉体征。神经放射学检查结果提示血管病变。文中讨论了与口服避孕药相关的脑血管疾病机制,尤其强调了外源性类固醇刺激引起内在血管病变的可能性。还指出了偏头痛、中风与口服避孕药之间的流行病学和病理生理关系。