[化脓性链球菌M蛋白免疫生物学的研究。IV. 恒河猴（猕猴）对链球菌抗原的细胞介导免疫（作者译）]
[Investigations about the immunobiology of m-proteins of Streptococcus pyogenes. IV. Cell-mediated immunity of rhesus monkeys (Macaca mulatta) against streptococcal antigens (author's transl)].
作者信息
Knöll H, Woskanjan N, Kühnemund O, Djikidse E K, Köhler W
出版信息
Allerg Immunol (Leipz). 1981;27(1):22-7.
PMID:6455052
Abstract
Cell-mediated immunity was tested in monkeys (Macaca mulatta) immunized with highly purified M-proteins by means of the lymphocyte transformation reaction. Lymphocytes from immunized and nonimmunized monkeys were stimulated with PAL-M-Proteins. IC-M-proteins were completely free of mitogenicity and no lymphocyte stimulation was to be found after immunization with 1.6 mg. Erythrogenic toxins of strain NY5 were able to stimulate lymphocytes of monkeys unspecifically.
摘要
通过淋巴细胞转化反应，对用高度纯化的M蛋白免疫的恒河猴（猕猴）的细胞介导免疫进行了测试。用PAL-M蛋白刺激免疫和未免疫猴子的淋巴细胞。IC-M蛋白完全无促有丝分裂活性，用1.6毫克免疫后未发现淋巴细胞刺激现象。NY5菌株的致热毒素能够非特异性地刺激猴子的淋巴细胞。
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