Navajas A, Pastor E, la Fuente P, Martínez P, Cabrera A
An Esp Pediatr. 1981 Jan;14(1):25-32.
Seven cases of isolated atrial septal defect, "ostium secundum" type, are presented. All had clinical symptoms of congestive heart failure and represented five per cent of the cases studied in our department with atrial septal defect. In three patients associated extracardiac anomalies were found. All had cardiomegaly, increased pulmonary vascularity, right ventricular hypertrophy and splitted second sound. Echocardiographic findings were: paradoxal movement of the interventricular septum and ventricular dyastolic overflow. Medium left to right shunt was 3.08. In four cases a massive filling of the right atrium was obtained, through, the selective injection of contrast material, in the pulmonary artery. None of the patients, responded to medical treatment alone and five of then went to surgery with significant improvement, in their clinical manifestations, and normal growth and weight curves in their follow-up. Importance in survival of early surgery is emphasized.
本文报告了7例孤立性房间隔缺损，“继发孔”型。所有患者均有充血性心力衰竭的临床症状，占我院房间隔缺损研究病例的5%。3例患者发现合并心外异常。所有患者均有心脏扩大、肺血管增多、右心室肥厚和第二心音分裂。超声心动图表现为：室间隔矛盾运动和心室舒张期充盈。左向右中等分流为3.08。4例患者通过选择性肺动脉造影剂注射，右心房大量充盈。所有患者单纯药物治疗均无效，其中5例接受手术治疗，临床表现显著改善，随访中生长和体重曲线正常。强调了早期手术对生存的重要性。
