Voyles C R, Richardson J D, Bland K I, Tobin G R, Flint L M, Polk H C
Ann Surg. 1981 Aug;194(2):219-23. doi: 10.1097/00000658-198108000-00017.
The acute replacement of full-thickness abdominal wall has been facilitated by polypropylene mesh (Marlex) (PPM), allowing debridement of nonviable tissue and restoration of abdominal wall integrity without tension. However, no substantial long-term follow-up has been reported on the definitive wound coverage after the use of PPM in open wounds. Since 1976, we have placed PPM in 31 patients; 25 for infectious complication, three for massive bowel distension preventing abdominal closure, and three for shotgun wounds with extensive tissue loss. In 29 of 31 patients, the mesh was placed in heavily contaminated wounds; extensive fasciitis was present in 23 patients and 21 had intra-abdominal abscesses. Following mesh placement, 23 reoperations were required for continuing complications. No patients eviscerated, despite these multiple procedures. Polypropylene mesh was highly effective in restoring abdominal wall continuity. Despite advantages when PPM was used, significant long-term problems developed. Seven patients died from their primary illness in the postoperative period. Nine wounds were closed by granulation and subsequent split-thickness skin grafts. All nine developed mesh extrusion and/or enteric fistulae. Nine wounds healed by secondary intention, six developed enteric fistulae or continuing mesh extrusion. Full-thickness flap coverage after granulation provided the best means of wound closure. Polypropylene mesh had significant early advantages for providing abdominal wall integrity even in the presence of severe infection. However, long-term problems were common when wounds were closed to skin grafts or secondary intention. If the mesh cannot be completely removed, strong consideration should be given to myocutaneous flaps for coverage after the primary illness has resolved.
聚丙烯网片(Marlex)(PPM)有助于急性全层腹壁置换,可对无活力组织进行清创,并在无张力的情况下恢复腹壁完整性。然而,关于在开放性伤口中使用PPM后最终伤口覆盖的长期随访报道并不多。自1976年以来,我们对31例患者使用了PPM;25例用于感染并发症,3例用于因大量肠扩张而无法关闭腹腔,3例用于组织大量缺失的霰弹枪伤。31例患者中有29例将网片置于严重污染的伤口中;23例患者存在广泛的筋膜炎,21例有腹腔内脓肿。放置网片后,因持续出现并发症需要进行23次再次手术。尽管进行了这些多次手术,但没有患者发生肠管脱出。聚丙烯网片在恢复腹壁连续性方面非常有效。尽管使用PPM有诸多优点,但仍出现了严重的长期问题。7例患者在术后因原发病死亡。9个伤口通过肉芽组织生长及随后的中厚皮片移植得以闭合。所有9例均出现网片外露和/或肠瘘。9个伤口通过二期愈合,其中6例出现肠瘘或网片持续外露。肉芽组织生长后的全厚皮瓣覆盖是伤口闭合的最佳方法。即使存在严重感染,聚丙烯网片在早期提供腹壁完整性方面仍具有显著优势。然而,当伤口通过皮片移植或二期愈合关闭时,长期问题很常见。如果无法完全取出网片,在原发病病情缓解后,应充分考虑采用肌皮瓣进行覆盖。