Cleary E G, Fanning J C, Prosser I
Connect Tissue Res. 1981;8(3-4):161-6. doi: 10.3109/03008208109152367.
On examination in the electron microscope elastic tissue is seen to consist of an amorphous component surrounded by microfibrillar components. The exact relationship between these components is unknown, although during development the microfibrils appear before the amorphous material. In this report we summarize our recent observations on the microfibrillar material. At high magnification the microfibrils are seen to have a poorly staining central core around the periphery of which are arranged more densely staining filaments which appear to wind around the microfibrils in a spiral fashion. Careful measurements of microfibrillar diameters from the aorta of four large species show that there are significant differences in the mean diameter and population distributions with species. The mean diameter of the microfibrils changes with age during fetal and postnatal development. The results of immunoelectronmicroscopic localization of an antibody to a microfibrillar component are reported and the possible roles of microfibrils in elastic tissue formation are examined.
在电子显微镜下观察，弹性组织由围绕着微原纤维成分的无定形成分组成。尽管在发育过程中微原纤维比无定形物质出现得早，但这些成分之间的确切关系尚不清楚。在本报告中，我们总结了我们最近对微原纤维物质的观察结果。在高倍放大下，可以看到微原纤维有一个染色较浅的中央核心，其周围排列着染色较密集的细丝，这些细丝似乎以螺旋方式缠绕在微原纤维周围。对四种大型物种主动脉微原纤维直径的仔细测量表明，平均直径和群体分布在物种之间存在显著差异。在胎儿期和出生后的发育过程中，微原纤维的平均直径会随着年龄的变化而改变。本文报道了针对微原纤维成分的抗体的免疫电子显微镜定位结果，并探讨了微原纤维在弹性组织形成中的可能作用。
