Bonoris P E, Greenberg P S, Castellanet M J, Ellestad M H
Am J Cardiol. 1978 May 1;41(5):846-51. doi: 10.1016/0002-9149(78)90723-3.
Coronary angiograms and treadmill stress tests were reviewed in 89 patients. Changes in R wave amplitude were measured in the control and immediate postexercise periods. Of 45 patients with normal coronary arteries, 41 (91 percent) had a decrease in R wave amplitude (P less than 0.01); 3 (7 percent) had an increase in amplitude, including 2 with abnormal left ventriculograms. The remaining patient (2 percent) had abnormal wall motion but no change in R wave amplitude. Among the 44 patients with significant coronary artery disease (70 percent or greater luminal narrowing in one or more vessels), R wave amplitude increased after exercise in 26 (59 percent) with more severe coronary artery disease. R wave amplitude decreased in 18 patients (41 percent) with normal or minimally abnormal resting ventriculograms and less severe coronary artery disease (P less than 0.01). Changes in R wave amplitude reflect ventricular function, an increase in R wave amplitude reflecting more severe dysfunction and severe coronary narrowing. A decreased R wave amplitude indicates normal or minimal dysfunction and is strongly associated with normal coronary angiograms.
对89例患者的冠状动脉造影和运动平板试验进行了回顾。在运动前和运动后即刻测量R波振幅的变化。45例冠状动脉正常的患者中，41例（91%）R波振幅降低（P<0.01）；3例（7%）振幅增加，其中2例左心室造影异常。其余1例患者（2%）有室壁运动异常但R波振幅无变化。在44例有显著冠状动脉疾病（一支或多支血管管腔狭窄70%或以上）的患者中，26例（59%）冠状动脉疾病较严重者运动后R波振幅增加。18例静息心室造影正常或轻度异常且冠状动脉疾病较轻的患者（41%）R波振幅降低（P<0.01）。R波振幅的变化反映心室功能，R波振幅增加反映功能障碍更严重和冠状动脉严重狭窄。R波振幅降低表明功能正常或轻度功能障碍，且与冠状动脉造影正常密切相关。
