Nosanchuk J S, Chang J, Bennett J M
Am J Clin Pathol. 1978 Apr;69(4):383-7. doi: 10.1093/ajcp/69.4.383.
Estimation of the platelet count from examination of peripheral blood smears is a widely practiced procedure, but statistical validity to judge the accuracy of the technic has been lacking. More than 400 patients' platelet estimates and counts were analyzed to develop a simple working formula to permit a reasonably accurate platelet estimate. Smear-to-smear and technician-to-technician variabilities were defined, and the influences of different microscopes on the platelet estimates were demonstrated. Platelet estimates can be used as a rapid, convenient measurement suitable for providing useful information for clinical judgement of a patient's platelet status providing that the method's limitations are recognized.
通过检查外周血涂片来估计血小板计数是一种广泛应用的方法，但一直缺乏判断该技术准确性的统计有效性。分析了400多名患者的血小板估计值和计数，以制定一个简单的实用公式，从而实现较为准确的血小板估计。确定了涂片间和技术人员间的差异，并证明了不同显微镜对血小板估计的影响。只要认识到该方法的局限性，血小板估计值可作为一种快速、便捷的测量方法，为临床判断患者血小板状态提供有用信息。
