de Guembecker W, Duriez J
Rev Chir Orthop Reparatrice Appar Mot. 1981;67(4):473-8.
The authors have observed 34 cases of Perthes' disease to try to discover whether the lesion is an isolated epiphyseal dystrophy or the local complication of a more generalised disease. They found that most of the patients show retardation of skeletal maturation without any of the usual pathological explanations. They consider that perthes' disease is associated with multiple factors including genetic and endocrinological ones causing generalised of cartilage.
作者观察了34例佩特兹病患者,试图确定该病变是孤立的骨骺发育不良,还是更广泛疾病的局部并发症。他们发现,大多数患者骨骼成熟延迟,且没有任何常见的病理学解释。他们认为佩特兹病与多种因素有关,包括导致软骨广泛性病变的遗传和内分泌因素。