Urban M D, Lee P A, Plotnick L P, Migeon C J
Am J Dis Child. 1978 May;132(5):494-7. doi: 10.1001/archpedi.1978.02120300054011.
We report the clinical and hormonal findings in two boys with isosexual precocity secondary to Levdig cell tumor of the testis. The hormonal profile at the initial evaluation was quite different in the two cases suggesting differences in steroid biosynthesis by the tumors. These differences indicate that a dexamethasone suppression test may be required to differentiate between Leydig cell tumors and congenital virilizing adrenal hyperplasia with adrenal rest tissue located within the testes.
我们报告了两名因睾丸间质细胞瘤导致同性性早熟男孩的临床和激素检查结果。两例患者初始评估时的激素水平差异较大，提示肿瘤的类固醇生物合成存在差异。这些差异表明，可能需要进行地塞米松抑制试验，以鉴别睾丸间质细胞瘤与伴有睾丸内肾上腺残余组织的先天性男性化肾上腺增生。
