[Biomorphosis of the human fallopian tube mucosa; a contribution to the problem of morphology and aging of the uterine tube. II. Histochemical findings].

The present histochemical findings of investigations on the biomorphosis of the human tubal mucosa indicate that mucosubstances and glycogen localized in the epithelium exhibit age-dependent changes with regard to occurrence and localization. In the embryo-fetal time PAS-positive, diastase-resistant substances are localized in the epithelium, at first basally, and later perinuclearly. In the neonatal phase the distal tubal epithelium has only a weak PAS reaction, and the proximal epithelium has a detectable supranuclear activity. In the end of the 1st decade of the life the epithelium possesses a periodate reactive diastase-sensitive material densely deposited in the preampullar and ampullar parts of the uterine tube, preferably. Afterwards PAS-positive diastase-sensitive and diastase-resistant substances, respectively, are regularly present, in which in the fertile age of the women a regular pattern of the PAS activity can be demonstrated. In the period of the regressive age it is possible to establish a increasing disturbance of the usual cellular picture of the tubal epithelium. In connection with the structural changes a increase of histochemical different reacting cell groups is evident. As a result, a dissociated cellular picture has developed. Epithelial glycoproteins and glycogen can be detected in the mucosa up to the phase of the senium.