Roux H, Aquaron R, Gaborit P, Bonnefoy-Cudraz M
Rev Rhum Mal Osteoartic. 1981 Jul-Sep;48(7-9):549-53.
The authors have been treating with a synthetic D penicillamine 12 patients affected with pains in the lumbar region or lumbosciaticas imputed to duroarachnoiditis in connection with surgical procedure or/and radiculosacography. The diagnosis is based on clinical arguments (3 cases), clinical and radiological arguments (radiculosacography : 3, phlebography : 3) and on surgical arguments (3 cases). The findings are good 5 times and incomplete twice. There are 4 failures and 3 interruption of treatment out of 6 intolerances. The effect of penicillamine upon collagen could perhaps be the explanation of these results.
作者用合成的D-青霉胺治疗了12例因手术操作或/和神经根造影检查导致硬脊膜蛛网膜炎而患有腰部疼痛或腰坐骨神经痛的患者。诊断基于临床依据(3例)、临床和放射学依据(神经根造影检查:3例,静脉造影:3例)以及手术依据(3例)。治疗效果良好5次,不完全有效2次。6例不耐受患者中有4例治疗失败,3例中断治疗。青霉胺对胶原蛋白的作用或许可以解释这些结果。