将毛发生长抑制作为筛选具有局部抗有丝分裂活性药物的一种方法。
Hair growth inhibition as a method of screening drugs for local antimitotic activity.
作者信息
Kaidbey K H
出版信息
J Invest Dermatol. 1977 Feb;68(2):70-2. doi: 10.1111/1523-1747.ep12491602.
PMID:64574
Abstract
The intradermal injection of certain drugs with antimitotic properties in the guinea pig resulted in localized areas of reversible hair loss or hair growth inhibition. The size of the affected field was related to the dose. This may provide a useful and simple method for the rapid screening of potentially useful agents for local cytostatic activity.
摘要
在豚鼠体内皮内注射某些具有抗有丝分裂特性的药物，会导致局部出现可逆性脱发或毛发生长抑制。受影响区域的大小与剂量有关。这可能为快速筛选具有潜在局部细胞抑制活性的有用药物提供一种有用且简单的方法。
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