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[暴露于高压氧后心肌的修复过程]

[Reparative processes in cardiac muscle following exposure to hyperbaric oxygenation].

作者信息

Makhova A N

出版信息

Arkh Anat Gistol Embriol. 1981 Jul;81(7):72-8.

PMID:6457590
Abstract

In 150 rabbits by means of histoautoradiographic, histochemical and certain histological methods, reparative processes in the cardiac muscle have been studied at experimental myocardial infarction and its combination with atherosclerosis under various regimes of hyperbaric oxygenation (HBO). It has been demonstrated that HBO (pO2--2 kgs/cm2, saturation time--45 min, 3-7 sessions) positively affects the proliferative processes in the ischemic zone, contributes to better preservation of the periinfarction parts of the myocardium and enhances maturation of the scar. If HBO is used in another regime (pO2--1 kgs/cm2, saturation time--30 min, 1-7 sessions), its positive effect on the regenerative processes in the ischemic zone is preserved, while its toxic effect on distant cardiac zones decreases considerably.

摘要

通过组织放射自显影、组织化学和某些组织学方法,在150只兔子身上研究了在不同高压氧疗(HBO)方案下,实验性心肌梗死及其与动脉粥样硬化合并时心肌的修复过程。结果表明,HBO(pO2 - 2千克/平方厘米,饱和时间 - 45分钟,3 - 7次疗程)对缺血区的增殖过程有积极影响,有助于更好地保存心肌梗死周边部分,并促进瘢痕成熟。如果采用另一种HBO方案(pO2 - 1千克/平方厘米,饱和时间 - 30分钟,1 - 7次疗程),其对缺血区再生过程的积极作用得以保留,而对心脏远处区域的毒性作用则显著降低。

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