Boué J, Barichard F, Deluchat C, Der Sarkissian H, Galano P, Boué A
Nouv Presse Med. 1981 Nov 7;10(40):3299-302.
A series of 226 antenatal diagnoses of chromosome structural re-arrangements in 181 couples has shown the usefulness of such diagnosis for couples including a genitor carrying a balanced anomaly. Analysis of the data has elicited major variations in the incidence of unbalanced anomalies in foetal cells and has provided information which can usefully be applied to genetic counselling.
对181对夫妇进行的226例染色体结构重排的产前诊断系列研究表明,这种诊断对包括携带平衡异常的父母在内的夫妇是有用的。对数据的分析揭示了胎儿细胞中不平衡异常发生率的重大差异,并提供了可有效应用于遗传咨询的信息。